Varicella is a 1999 work of interactive fiction by Adam Cadre, distributed in z-code format as freeware. It is set in an alternate history which features roughly modern technology mixed with Renaissance-style principalities and court politics. The characters of Varicella use contemporary language from their home in a Renaissance castle, continuing the contrast between old and new. The player character is Primo Varicella, palace minister in Piedmont, who has to get rid of several rivals for the regency following the death of the king. The international situation in the game is described in passing: Piedmont is part of a loose confederation of kingdoms that make up a Carolingian League and is engaged in a war against the Republic of Venice.

It won four XYZZY Awards in 1999 including the XYZZY Award for Best Game, and was nominated for another four.